Sep. 12, 2024
2024 The Safety Pharmacology Society Annual Meeting
Town and Country Resort, San Diego, CA - September 22-25
The conference
website
https://web.cvent.com/event/003da1c0-d8aa-41cc-9390-ca9257bbcbe7/websitePage:c0a0dbc1-1c39-48e1-9582-80ecb5b18289
Human-induced
pluripotent stem cell-derived cells (hiPSC) are expected to have applications
in the fields of regenerative medicine and drug discovery. Due to the recent trend of reducing
or eliminating animal testing, hiPSC is also expanded to use as the alternative
method for animal testing. Human-induced pluripotent stem cell-derived
cardiomyocytes (hiPS-CMs) are especially effective as an alternative assay of
human cardiomyocytes which are not easily available.
hiPS-CMs are,
however, considered immature, hence the maturation of hiPS-CMs is an important
issue for proper assessment of drug response. To induce maturation of hiPS-CMs,
various methods have been developed, including long-term culturing,
three-dimensional (3D) tissue engineering, mechanical loading, electrical
stimulation, modulation of substrate stiffness, and treatment with
neurohormonal factors. In
these context, we attempted an anisotropic orientation
culture, in which the cultured cells are aligned in one orientation resembling
in vivo cardiomyocytes. Culture substrate for anisotropic orientation culture
was developed by applying our original nanofabrication technology
(CellArray-Heart™, Oji Holdings Corporation) , and the
alignment and maturation of hiPS-CMs were evaluated with the culture substrate.
Visit us at our
poster
Don’t miss the poster session discussing
our innovative culture device “CellArray-Heart™”
Poster:
"Application for Drug evaluation of Human-Induced Pluripotent Stem
Cell-Derived Cardiomyocytes Cultured by Anisotropic Orientation"
Poster No.: #041-A
About the Meeting
The Safety
Pharmacology Society (SPS) Annual Meeting is a significant event in the field
of safety pharmacology. The 2024 Annual Meeting will be held from September 22
to 25 at the Town and Country Resort in San Diego, California.
At this
conference, the latest research findings and technological innovations will be
presented. Participants can deepen their knowledge through workshops and panel
discussions.
[Contact about “CellArray-Heart™”]
ohd-cellarray@oji-gr.com